Distribution and phenotypes of hemifacial microsomia and its association with other anomalies
양일형, 정지혁, 임선진, 조일식, 임승원, Kim Ki-Kap, 김석화, 최진영, 이종호, 김명진, 백승학,
소속 상세정보
양일형 ( Yang Il-Hyung ) - Seoul National University School of Dentistry Department of Orthodontics
정지혁 ( Chung Jee-Hyeok ) - Myongji Hospital Department of Plastic and Reconstructive Surgery
임선진 ( Yim Sun-Jin ) - Seoul National University School of Dentistry Department of Orthodontics
조일식 ( Cho Il-Sik ) - Private practice
임승원 ( Lim Seung-Weon ) - Chonnam National University School of Dentistry Department of Orthodontics
( Kim Ki-Kap ) - Private practice
김석화 ( Kim Suk-Wha ) - Seoul National University College of Medicine Department of Plastic and Reconstructive Surgery
최진영 ( Choi Jin-Young ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Surgery
이종호 ( Lee Jong-Ho ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Surgery
김명진 ( Kim Myung-Jin ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Surgery
백승학 ( Baek Seung-Hak ) - Seoul National University School of Dentistry Department of Orthodontics
Abstract
Objective: To investigate the distribution and phenotypes of hemifacial microsomia (HFM) and its association with other anomalies.
Methods: This study included 249 Korean patients with HFM, whose charts, photographs, radiographs, and/or computed tomography scans acquired during 1998?2018 were available from Seoul National University Hospital and Dental Hospital. Prevalence according to sex, side involvement, degree of mandibular deformity, compensatory growth of the mandibular body, and Angle’s classification, and its association with other anomalies were statistically analyzed.
Results: Prevalence was not different between male and female patients (55.0% vs. 45.0%, p > 0.05). Unilateral HFM (UHFM) was more prevalent than bilateral HFM (BHFM) (86.3% vs. 13.7%, p < 0.001). Although distribution of the Pruzansky?Kaban types differed significantly in patients with UHFM (I, 53.0%; IIa, 18.6%; IIb, 24.7%; III, 3.7%; p < 0.001), no difference was observed in occurrence between the right and left sides (52.6% vs. 47.4%, p > 0.05). Among patients with BHFM, prevalence of different Pruzansky?Kaban types on the right and left sides was greater than that of the same type on both sides (67.6% vs. 32.4%, p < 0.05). Despite hypoplasia of the condyle/ramus complex, compensatory growth of the mandibular body on the ipsilateral side occurred in 35 patients (14.1%). Class I and II molar relationships were more prevalent than Class III molar relationships (93.2% vs. 6.8%, p < 0.001). Forty-eight patients (19.3%) had other anomalies, with 50.0% and 14.4% in the BHFM and UHFM groups (p < 0.001).
Conclusions: Patients with HFM require individualized diagnosis and treatment planning because of diverse phenotypes and associations with other anomalies.
키워드
Distribution; Phenotype; Hemifacial macrosomia; Association with other anomalies
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